General Description
D-Panthenol, also known as Provitamin B5, is a highly effective moisturizing and conditioning agent widely used in cosmetic and personal care formulations. It is the biologically active enantiomer of Panthenol and is converted in the skin into pantothenic acid (Vitamin B5), an essential component for maintaining healthy skin and hair. D-Panthenol is a colorless, viscous liquid or crystalline powder, soluble in water and alcohol, making it easy to incorporate into a variety of formulations. It is valued for its hydrating, soothing, and healing properties, which help to improve the overall health and appearance of skin and hair.
Uses in the Cosmetics Industry
D-Panthenol is a multifunctional ingredient with widespread applications in personal care products:
- Skin Care (Creams, Lotions, Serums): Provides deep hydration, reduces transepidermal water loss (TEWL), and enhances skin softness and elasticity.
- Hair Care (Shampoos, Conditioners, Treatments): Improves hair moisture retention, adds shine, and strengthens hair fibers to reduce breakage.
- Wound-Healing & Soothing Products: Used in after-sun lotions, baby creams, and soothing balms due to its skin-repairing and anti-inflammatory effects.
- Makeup Products: Helps improve the smoothness and spreadability of cosmetic formulations while keeping skin moisturized.
- Nail Care: Strengthens nails and helps prevent brittleness.
Its gentle, non-irritating profile makes D-Panthenol highly suitable for sensitive skin and baby care formulations.
Hazards
D-Panthenol is generally recognized as safe, non-toxic, and well-tolerated in cosmetic applications. However, a few considerations apply:
- Skin Reactions: Rare cases of mild irritation or allergic reactions have been reported, particularly in individuals with hypersensitive skin.
- Eye Contact: May cause temporary irritation if accidentally introduced into the eyes in high concentrations.
- Formulation Limits: Excessive concentrations may lead to stickiness in topical products, affecting user experience rather than safety.
With proper formulation practices, D-Panthenol is regarded as one of the safest and most effective active ingredients in cosmetics.
CAS Number: 81-13-0
INCI: Panthenol
Composition: D-Panthenol is the dextrorotatory isomer of panthenol (provitamin B5). It is a stable alcohol analogue of pantothenic acid, readily converted into pantothenic acid (Vitamin B5) in the skin and hair.
Purity Grade: Cosmetic and Pharmaceutical Grade
Appearance: Clear, colorless to slightly yellow, viscous liquid
Solubility: Freely soluble in water, ethanol, and propylene glycol; insoluble in oils and fats
Preservation: D-Panthenol itself is chemically stable and does not require preservatives in raw material form. In formulations, preservation depends on system composition.
Storage: Store in a tightly closed container in a cool, dry, and well-ventilated place. Protect from light and excessive heat to maintain stability.
Raw Material Sources: Produced synthetically from petrochemical-derived or glucose-based intermediates, then refined to high purity.
Manufacture: Industrially synthesized via controlled chemical synthesis and purification, ensuring high purity of the dextrorotatory isomer (D-form).
Animal Testing: Not animal tested
GMO: GMO-free (synthetic origin)
Vegan: Does not contain animal-derived components
Proposition: D-PANTHENOL complies with cosmetic and pharmaceutical regulatory requirements, including EU Cosmetic Regulation and U.S. FDA guidelines.
Warning: Avoid direct eye contact. Use gloves and protective equipment during handling in raw form. For external use in cosmetic and pharmaceutical applications only.
