
THE STORY OF BENZOPHENONE 3
Benzophenone-3: Broad-Spectrum UV Protection in a Single Molecule
Benzophenone-3 (2-Hydroxy-4-methoxybenzophenone) is a highly efficient organic UV filter and photostabiliser. It absorbs both UVB and portions of UVA rays, helping prevent sunburn, photodamage and premature aging in skin.
Synthesised for Precision: High Purity UV-Filter
Benzophenone-3 is produced via a controlled synthesis route (e.g., Friedel-Crafts reaction) and then purified into crystalline form for use in cosmetics and sunscreens. It is supplied as a pale yellow solid with excellent solubility in oil phases
Shielding Skin from the Sun: Performance & Versatility
Benzophenone-3 delivers key benefits in sun care formulations:
• Strong UVB + partial UVA absorption, contributing to broad-spectrum protection.
• Acts as a photostabiliser for other filters and active ingredients, enhancing product longevity.
• Oil-soluble, easy to incorporate in emulsions, creams, sprays and lip balms.
Used widely in daily sunscreens, anti-age serums, lip protection and sun-exposed body care.
Effective, but Requires Care: Regulatory & Formulation Guidelines
• Usage limits vary by market — for example up to ~6% in EU sunscreens.
• Store in a cool, dry, light-protected environment to preserve stability.
• Although effective, studies highlight concerns: systemic absorption, endocrine disruption potential, coral reef impact.
• Formulators should ensure compatibility with other filters, stabilisers, and ensure batch COA and safety data are compliant.
Formulator’s Queries, We Answered
1. What is Benzophenone-3 (Oxybenzone)?
Benzophenone-3, also known as Oxybenzone, is an organic UV filter commonly used in sunscreens and personal care products. It absorbs UVB and short-wave UVA rays, helping to protect the skin from sun damage and photoaging.
2. What is the CAS number and INCI name of Benzophenone-3?
CAS Number: 131-57-7
INCI Name: Benzophenone-3 (Oxybenzone)
3. What are the benefits of Benzophenone-3 in personal care?
Benzophenone-3 is widely used because of its:
UV protection: Shields the skin from harmful UVB and UVA II rays.
Photo-stabilizing effect: Enhances the stability of other UV filters.
Prevention of premature aging: Reduces sun-induced skin damage.
Protection of product formulations: Prevents degradation of cosmetic products exposed to sunlight.
4. How does Benzophenone-3 work in sunscreens?
Benzophenone-3 works by absorbing UV radiation and converting it into less harmful heat energy, preventing DNA damage and photoaging. It is often combined with other sunscreen agents for broad-spectrum protection.
5. Is Benzophenone-3 suitable for all skin types?
While effective, some individuals with sensitive or reactive skin may experience irritation or allergic reactions. Patch testing is recommended before use.
6. What types of personal care products contain Benzophenone-3?
Benzophenone-3 is found in:
Sunscreens (creams, sprays, lotions)
Moisturizers with SPF
Lip balms with UV protection
Hair care products (UV-protective shampoos and sprays)
Nail polishes (to prevent discoloration)
7. Can Benzophenone-3 be combined with other UV filters?
Yes, Benzophenone-3 is often formulated with:
Avobenzone (for extended UVA protection)
Homosalate & Octisalate (to boost SPF effectiveness)
Octinoxate & Octocrylene (to improve photostability)
8. Does Benzophenone-3 cause any side effects?
Benzophenone-3 is generally safe but may cause:
Skin irritation in sensitive individuals.
Hormonal concerns: Some studies suggest it may have mild endocrine-disrupting effects.
Allergic reactions: Rare but possible for some skin types.
9. What is the recommended concentration of Benzophenone-3 in sunscreens?
Up to 6% in the United States (FDA limit).
Up to 10% in the European Union and other regions.
10. Is Benzophenone-3 reef-safe?
Benzophenone-3 has been linked to coral reef damage and is banned in some locations (e.g., Hawaii, Palau). Reef-safe alternatives include Zinc Oxide and Titanium Dioxide.
11. Where can I purchase high-quality Benzophenone-3 for formulation purposes?
Benzophenone-3 is available from cosmetic raw material suppliers. Always select high-purity and UV-stabilized grades for optimal performance in formulations.