
THE STORY OF L-GLUTATHIONE REDUCED
L-Glutathione Reduced: The Master Antioxidant for Bright, Clear & Youthful Skin
L-Glutathione (Reduced) is a powerful tripeptide antioxidant known for its ability to brighten skin, reduce oxidative stress, and support even skin tone.
Naturally present in the body, cosmetic-grade Glutathione helps combat free radicals, promoting radiance, clarity, and anti-aging benefits in topical skincare products.
A Bioactive Tripeptide Produced via Fermentation for Superior Skin Performance
L-Glutathione is composed of three amino acids:
• L-Glutamic Acid
• L-Cysteine
• Glycine
The reduced form (GSH) is the biologically active antioxidant form.
Produced using yeast fermentation or enzymatic synthesis, it is then purified into a stable crystalline powder.
TRCkem supplies high-purity, cosmetic-grade L-Glutathione Reduced for advanced skincare formulations.
Brighten. Defend. Rejuvenate.
L-Glutathione delivers multiple skin-enhancing benefits:
✅ Reduces dark spots, melasma & uneven pigmentation
✅ Provides potent antioxidant protection
✅ Supports brighter, more luminous complexion
✅ Helps slow visible signs of aging
✓ Synergizes with Vitamin C & Niacinamide for boosted brightening
Used in: brightening serums, day/night creams, eye gels, anti-pollution skincare, face masks & spot-correcting formulas.
Potent Antioxidant — Use in Stabilized, pH-Balanced Skincare Systems
• Typical use level: 0.1–2% depending on product type
• Best used in formulations with pH 4–6
• Sensitive to oxidation — requires antioxidants or air-tight packaging
• Add during cool-down phase (<40°C) to maintain activity
• Store in airtight, moisture-free containers away from light
• Safe for topical cosmetic use when formulated correctly
• Works best when combined with other brightening actives
Formulator’s Queries, We Answered
1. What is L-Glutathione Reduced?
L-Glutathione Reduced (GSH) is a naturally occurring tripeptide composed of glutamic acid, cysteine, and glycine. It functions as a potent antioxidant, protecting cells from oxidative stress and free radical damage. In personal care products, GSH is valued for its skin-brightening, anti-aging, and detoxifying properties.
2. What are the CAS Number and INCI Name of L-Glutathione Reduced?
CAS Number: 70-18-8
INCI Name: Glutathione
3. What are the benefits of using L-Glutathione Reduced in personal care products?
L-Glutathione Reduced offers several benefits for skin health:
Skin Brightening: Helps reduce melanin production, leading to a lighter and more even skin tone.
Anti-Aging: Neutralizes free radicals, reducing the appearance of wrinkles and fine lines.
Detoxification: Supports the body's natural detox processes, promoting clearer skin.
Improved Skin Elasticity: Enhances skin firmness and elasticity, contributing to a youthful appearance.
4. What are the common applications of L-Glutathione Reduced in personal care?
L-Glutathione Reduced is incorporated into various personal care products, including:
Skin Lightening Creams and Serums: To promote a brighter complexion.
Anti-Aging Formulations: To combat signs of aging and improve skin texture.
Detoxifying Masks and Treatments: To cleanse and rejuvenate the skin.
Oral Supplements: To support overall skin health from within.
5. Is L-Glutathione Reduced safe for use in personal care products?
Yes, L-Glutathione Reduced is generally considered safe for topical and oral use in personal care products. However, it's essential to use it within recommended concentrations and consult with a dermatologist or healthcare professional before starting any new skincare regimen.
6. Can L-Glutathione Reduced cause skin irritation?
L-Glutathione Reduced is typically well-tolerated. However, individuals with sensitive skin may experience mild irritation. It's advisable to perform a patch test before applying products containing GSH extensively.
7. Is L-Glutathione Reduced environmentally friendly?
As a naturally occurring compound, L-Glutathione Reduced is biodegradable and poses minimal environmental risks when used in personal care products.
8. Are there alternatives to L-Glutathione Reduced in personal care products?
Yes, alternatives include:
Vitamin C (Ascorbic Acid): A potent antioxidant that brightens skin and promotes collagen production.
Niacinamide (Vitamin B3): Improves skin elasticity and enhances barrier function.
Alpha Arbutin: Reduces melanin production, leading to a more even skin tone.
Licorice Extract: Contains glabridin, which helps in skin brightening and soothing.